Buspar and Buspirone

BuSpar (buspirone hydrochloride) is an antianxiety agent that is not chemically or pharmacologically related to the benzodiazepines, barbiturates, or other sedative/anxiolytic drugs.

An anxiolytic agent and a serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the benzodiazepines, but it has an efficacy comparable to DIAZEPAM.

It is used primarily as an anxiolytic, but also to a lesser extent as an antidepressant. Bristol-Myers Squibb gained FDA approval for buspirone in 1986, and it went generic in 2001.

Rarely, buspirone's side effects may have a dangerous nature or intensity. Some tend to disappear with continued therapy, or are less frequent if the initial dose is low and increased gradually.

BuSpar is supplied for oral administration in 5 mg and 10 mg, white, ovoid-rectangular, scored tablets.

• Tablets 5 mg (4.6 mg as base)
• Tablets 10 mg (9.1 mg as base)
• Tablets 15 mg (13.7 mg as base)
• Tablets 30 mg (27.4 mg as base)